The detainees, many wielding sticks, broke free from the center near the port city of Haiphong in northeast Vietnam late Sunday.
“More than 400 inmates fled after breaking the door and threatened the guards of the center with sticks,” Nguyen Huy Hoang, an official from Thuy Nguyen district — where the center is located — told AFP.
Police found some of the addicts back at their homes, while around 30 others voluntarily returned to the treatment center.
“The police are searching for those who are still at large,” in Haiphong, the third largest city in Vietnam, Hoang added.
The communist government enforces the compulsory treatment program for the country’s estimated 140,000 drug addicts.
Addicts must undergo two-year spells of “rehabilitation” in what the government describes as an effort to bring down rising rates of drug use, especially among young people.
The treatment period at the Gia Minh center, where the breakout took place, was recently extended to three years, Hoang said.
The center has also reduced the amount the amount of money spent on food, prompting complaints from the addicts, he added.
In May 2010 and April 2012, detainees at similar addiction treatment centers in Haiphong also staged breakouts.
US-based Human Rights Watch has denounced the conditions in Vietnam’s rehab centers and a UN expert has recommended they be closed.
HRW says the treatment centers are “forced labor camps” where inmates do not receive proper health care and are often subjected to physical violence.
Addicts are mostly forced to report to the centers by their family or local authorities, but they are not criminals.
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