NEW YORK -- (UPDATE 3) All 48 passengers and crew, plus one person on the ground, were killed when a plane crashed into a house outside Buffalo, New York on Thursday and burst into flames, officials said.

State police spokeswoman Rebecca Gibbons told US media that there were 48 people on the plane and "there were no survivors." A county official had earlier confirmed one fatality on the ground.

An Erie County official said Continental Airlines flight 3407 crashed at 10:20 p.m. (0320 GMT) in the town of Clarence Center, New York, about five minutes before it was due to land at the Buffalo airport.

"One structure has been seriously damaged and the aircraft is currently still burning -- somewhat under control," David Bissonette, emergency coordinator in Clarence Center told reporters. "We have multiple fatalities. The scene is secured by the state police and a long-term investigation is imminent."

One county official said he was not aware of any reports of trouble from the plane.

"I was told the plane simply dropped off the radar screen," the official said.

US media showed footage of the smoking wreckage in the center of a residential neighborhood.

A man who gave his name only as Tony told a local television station that the plane flew right over his car, "nose down."

"Left wing was slightly down, pitched sideways, if you will," he said. "It was on a direct line down."